This paper covers the findings of three decades of research into the synthesis, chemistry, and synthetic uses of ciscyclohexadienediols derived from arenes via biotransformation. These cisdiols are excellent chiral building blocks because they are enantiomerically pure, have high chemical flexibility, and are easily accessible. Natural phenazines are significant secondary metabolites with wide antibacterial bioactivity. However, because to the limited substitution of side groups, the bioactivity diversity of phenazines is very limited.

Because of the presence of enzymes such as lipoxygenases, the mycelium of Pleurotus sapidus can be employed as a biocatalyst for organic biosynthesis. The goal of this study was to improve the pesticide effect of - and -pinenes, the primary components of essential oils from Pinus spp., through the bioconversion process. Cytochrome P450 enzymes (CYPs) are one of the most essential oxidative enzyme families in the human body, responsible for the metabolism of a wide range of foreign and endogenous substrates. To gain a better understanding of the selectivity of these enzymes and to obtain new natural products. Modeling experiments explain these discrepancies by comparing the geometries of the binding pockets to the non-oxidized alkyl chain.